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Comparison of Treatments

Issue
ReTEAR
Xiidra
Restasis
Improvement of Symptoms

Fast
1 hour to 1 day 

95% of patients improve

Slow
2 weeks to 1 month 

15% of patients improve

Slowest

3 months 

15% of patients improve


Average Cost

$175/month.

$675/month. *

$715/month. *

Dosing

1 or 2 times/day

2 times/day,

12 hrs apart

2 times/day,

12 hrs apart

Side Effects


NONE **


Burning, Redness, Blurry, 

Metalic Taste, Loss of Taste

Burning, Red Eye, Pain, 

Blurry Vision, Swelling

Formulation & Application method

Cream applied 

to eyelid skin surface

Eye drops inside the eye


Eye drops inside the eye


Mode of Action

Activates

natural tear production

Inhibits immune

system T cells

Suppresses immune

system T cells

Contact lens precautions

Can use while wearing contacts

Do NOT use while wearing contacts ***

Do NOT use while wearing contacts ***

Source of Medication & Active Ingredient

Natural herb 

(Jaborandi/Pilocarpine) 

from Amazon Rainforest. 

Lifitegrast

Synthasized in a laboratory


Fungus 

(Trichoderma Polysporum)

Cyclosporine-A eye drops

In use since

The 1870's

July, 2016

October, 2003

Not covered by MSP or insurance. Approximate price per GoodRx.

**Super sensitive skin to makeup or skin care products can show irritation

*** Wait 15 minutes after using Xiidra before you put in your contacts

*** Wait 15 minutes after using Restasis before you put in your contacts

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